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found that cardiac microvascular endothelial cells isolated from T2DM mice exhibited increased expression of pro-ferroptotic genes (Tfrc, Acsl4, Ptgs2), decreased expression of anti-ferroptotic genes (Gpx4, Slc7a11), and elevated lipid peroxidation (MDA, 4-HNE), indicating that hyperglycemia also induces ferroptosis in endothelial cells [97]

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According to his study, although probiotics are primarily safe to be consumed and socially help patients, they are proposed not to receive the negative stigma associated with standard antidepressants